fodlder 发表于 2025-3-30 10:13:21
https://doi.org/10.1007/978-3-030-42882-2LH (henceforth referred to as “pHLH”) and are the focus of this chapter. Conversely, secondary HLH (sHLH) often occurs in the absence of monogenic etiologies that are commonly associated with pHLH and can be triggered by infections, malignancies, or rheumatological diseases; these triggers and the gIngenuity 发表于 2025-3-30 15:21:10
http://reply.papertrans.cn/25/2427/242633/242633_52.png的染料 发表于 2025-3-30 19:00:35
https://doi.org/10.1007/978-3-030-42882-2sible for the frequently fatal multiorgan system failure seen in MAS. Whole exome sequencing as well as targeted sequencing of pHLH-associated genes in patients with SJIA-associated MAS demonstrated increased “burden” of rare protein-altering variants affecting the cytolytic pathway compared to healnovelty 发表于 2025-3-30 22:21:55
http://reply.papertrans.cn/25/2427/242633/242633_54.pngGLARE 发表于 2025-3-31 01:26:20
http://reply.papertrans.cn/25/2427/242633/242633_55.png欺骗手段 发表于 2025-3-31 05:18:33
History of Hemophagocytic Lymphohistiocytosiseceiving increased attention. The history of HLH dates back to 1939 when it was first described in adults, to be followed in 1952 by the first description of its primary, familial form in children. Secondary forms of HLH are far more frequent and occur with infections, malignancies, metabolic diseasCredence 发表于 2025-3-31 12:53:35
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