惰性气体
发表于 2025-3-28 18:35:57
https://doi.org/10.1007/978-981-13-7693-1. The reductase was subsequently found to be located in the microsomal fraction (. and . 1962; . and . 1962). These earlier findings provided the setting for raising a number of questions concerning reductase function: Since cytochrome . is located in the mitochondria, what is the physiological subs
chronology
发表于 2025-3-28 20:10:45
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poliosis
发表于 2025-3-28 23:57:12
Combinatorial chemistry: A perspectiveenerating system. This simple reconstitution system has been found to be very reproducible, so that data from different laboratories can often be easily compared if the same incubation conditions have been used.
不要严酷
发表于 2025-3-29 03:40:04
Brian K. Kay,Andrew D. Ellingtonendent upon the presence of a particular metal, ligand structure, or solvent. Indeed, much has been inferred about the catalytic mechanism of the enzyme from studies with these models (. et al. 1989) because some of the postulated enzyme intermediates are probably inaccessible for direct observation
捐助
发表于 2025-3-29 08:42:50
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饰带
发表于 2025-3-29 12:52:46
https://doi.org/10.1007/978-3-662-11155-0ular cytochrome P450 enzyme and thus whether its plasma concentration and, consequently, its therapeutic effects may be subjected to interindividual variations of the activity of this enzyme. Likewise, more knowledge about structural features of compounds inhibitory for cytochrome P450 enzymes is re
Gesture
发表于 2025-3-29 18:31:22
Historical Background and Description of the Cytochrome P450 Monooxygenase System as well as work from Miller’s laboratory (. and . 1953), it became clear that liver microsomes were the source of NADPH-dependent, oxidative enzymes capable of metabolizing a number of xenobiotic compounds. Since the 1950s more than 800 different xenobiotics, ranging from drugs to organic chemicals
闲逛
发表于 2025-3-29 22:14:06
NADPH-Cytochrome P450 Reductase: Function. The reductase was subsequently found to be located in the microsomal fraction (. and . 1962; . and . 1962). These earlier findings provided the setting for raising a number of questions concerning reductase function: Since cytochrome . is located in the mitochondria, what is the physiological subs
judiciousness
发表于 2025-3-30 00:58:31
Protein and Gene Structure and Regulation of NADPH-Cytochrome P450 Oxidoreductase toxicity of these compounds (. et al. 1978, 1979), while electron transfer to mitomycin C produces the active form of this antitumor compound (. et al. 1984). in conjunction with EDTA-Fe., cytochrome P450 or O.., the reductase can initiate microsomal lipid peroxidation (. et al. 1973; reviewed by .
痛恨
发表于 2025-3-30 07:51:16
Localization of Cytochrome P450 in Membranes: Reconstituted Systemsenerating system. This simple reconstitution system has been found to be very reproducible, so that data from different laboratories can often be easily compared if the same incubation conditions have been used.