序曲 发表于 2025-3-25 05:56:33
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978-1-0716-3948-1The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines阻挡 发表于 2025-3-25 11:38:59
Cell Culture and Slide Preparation for Cytogenetic Studies of Hematological Neoplasmse essential steps to enrich and collect sufficient neoplastic cells for cytogenetic studies of the neoplasms. This chapter describes methods that are commonly used for culturing hematological neoplastic cells and preparing cytogenetic slides for clinical diagnosis and research of the neoplasms.CAB 发表于 2025-3-25 17:08:38
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Mahdi Fahmideh,Farhad Daneshgar,Fethi Rabhicytogenetic analyses. It is suggested that DNA sequencing provides high resolution, speed, and automation, potentially replacing cytogenetic testing. We disagree with this reductionist prediction. On the contrary, various sequencing projects have unexpectedly challenged gene theory and highlighted tKeratectomy 发表于 2025-3-26 03:19:48
Patterns for Workflow Engine Benchmarkingor “complex” (with more than two breakpoints). Studying the breakpoints of SVs at nucleotide resolution revealed additional, subtle structural variations, such that even “simple” SVs turned out to be “complex.” Genome-wide sequencing methods, such as fosmid and paired-end mapping, short-read and lonInterstellar 发表于 2025-3-26 07:41:53
Simon Harrer,Oliver Kopp,Jörg Lenhardcompassing chromosomal mosaicism and instability) in cancer yields paradoxical results. Firstly, somatic mosaicism for specific chromosomal rearrangement causes cancer per se. Secondly, chromosomal mosaicism and instability are associated with a variety of diseases (chromosomal disorders demonstratiInoperable 发表于 2025-3-26 09:53:05
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Service Network Modeling: A Generic Approachave been used to compare various other cytogenetic and cytogenomic technologies, including karyotype, microarrays, and DNA sequencing, with impressive results. In this chapter, using OGM as a case study, we advocate for a new trend in future cytogenomics, emphasizing the power of machine automationdrusen 发表于 2025-3-26 18:43:18
Azlan Ismail,Valeria Cardellinie essential steps to enrich and collect sufficient neoplastic cells for cytogenetic studies of the neoplasms. This chapter describes methods that are commonly used for culturing hematological neoplastic cells and preparing cytogenetic slides for clinical diagnosis and research of the neoplasms.