变态 发表于 2025-3-23 12:26:11
Monique Frize,Claire Deschênes,Ruby Heap the diversity of the earliest events that trigger neurodegeneration, and that eventually result in senile plaques (SP) and neurofibrillary tangles (NFTs). The original version of the most commonly held amyloid hypothesis rests on the concept that amyloid-β (Aβ). self-polymerizes over many years toLIEN 发表于 2025-3-23 15:48:28
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Women Vloggers, Cultures & Natures, Parkinson’s, Huntington’s, and prion diseases), as well as several systemic amyloidosis. Among them, prion disease are the only one known to be infectious. Current evidence shows that the infectious agent in prion diseases is the misfolded protein and that the molecular mechanisms responsible forTexture 发表于 2025-3-24 02:37:55
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http://image.papertrans.cn/d/image/241190.jpg不再流行 发表于 2025-3-24 12:19:57
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What Have We Learned from the Tau Hypothesis?ss, neuroinflammation, immune deregulation, impairment of neuronal-glial communication, and neurotoxic agents appear to be the major factors triggering neuronal degeneration, and the balance among these seems to vary from patient to patient. Although diverse, these factors induce deleterious signali