nourish 发表于 2025-3-21 19:35:30

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奴才 发表于 2025-3-21 22:19:11

Wnt Signaling in Osteosarcomaonal co-activator β-catenin, which ultimately controls key developmental gene expressions. Given the central role of this mediator, inhibition of Wnt/β-catenin signaling has been investigated as a potential strategy for cancer control. In OS, several secreted protein families modulate the Wnt/β-cate

极小 发表于 2025-3-22 01:45:05

Receptor Tyrosine Kinases in Osteosarcoma: Not Just the Usual Suspectse then validated using independent validation experiments. From these results, we identified four RTKs (Axl, EphB2, FGFR2, and Ret) that have not been previously studied in osteosarcoma and provide targets for the development of novel therapeutics.

慢慢冲刷 发表于 2025-3-22 05:56:12

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奴才 发表于 2025-3-22 09:47:21

Developmental Pathways Hijacked by OsteosarcomaThis pathway also helps regulate expression of the mature osteoblast protein osteocalcin. YAP also regulates expression of MT1-MMP, a membrane-bound matrix metalloprotease responsible for remodeling the extracellular matrix surrounding the osteoblasts. YAP, in turn, can be regulated by the ERBB fami

政府 发表于 2025-3-22 15:22:25

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政府 发表于 2025-3-22 19:00:15

Role of Ezrin in Osteosarcoma Metastasis protein that associated with OS and other cancers. Ezrin is the prototypical ERM (Ezrin/Radixin/Moesin) protein family member. ERMs function as linker proteins connecting the actin cytoskeleton and the plasma membrane. Since our initial identification of ezrin in pediatric sarcoma, an increasing un

轻快来事 发表于 2025-3-22 22:31:55

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独白 发表于 2025-3-23 02:14:15

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催眠药 发表于 2025-3-23 08:48:30

Using Canine Osteosarcoma as a Model to Assess Efficacy of Novel Therapies: Can Old Dogs Teach Us Nethout chemotherapy that could not be done in humans with osteosarcoma due to ethical concerns. This chapter will focus on the novel therapies in the dog that have been reported or are in veterinary clinical trials at the author’s institution. It is hoped that collaboration between veterinary oncolog
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查看完整版本: Titlebook: Current Advances in Osteosarcoma; Eugenie S. Kleinerman, M.D. Book 20141st edition Springer Nature Switzerland AG 2014 bone cancer.cancer.