啤酒
发表于 2025-3-30 11:59:04
Prediction of Protein Structure from Amino Acid Sequencecently, the advent of protein engineering has increased the requirements to model the relationship between protein sequence and conformation (eg. Fersht et al, 1985). This paper reviews available methods of structure prediction and introduces developments using data bases and logic programming computer languages.
肉体
发表于 2025-3-30 14:28:27
The Water Structure in 2Zn Insulin Crystalsen well ordered by contacts to the protein, and move extensively along the connected networks across the protein. Where there are few specific sites with suitable H bond and other contacts the water molecules exist in a practically continuous population of networks (J Finney, et al., 1982).
不舒服
发表于 2025-3-30 16:43:15
These problems have motivated efforts to supplement or replace MIR as a phasing technique. Various approaches have been tried, both in real and reciprocal space, and among them DM (density modification) methods have proven to be quite succesful in improving phases using real-space constraints.
曲解
发表于 2025-3-30 21:12:23
is better than 2 Angstrom which is sufficient for the recognition of the amino-acid residues of a polypeptide chain. With the electron microscope being such an ideal instrument for the elucidation of protein structure, one would wonder why X-ray crystallography still exists.
GILD
发表于 2025-3-31 00:58:59
Density Modification MethodsThese problems have motivated efforts to supplement or replace MIR as a phasing technique. Various approaches have been tried, both in real and reciprocal space, and among them DM (density modification) methods have proven to be quite succesful in improving phases using real-space constraints.
badinage
发表于 2025-3-31 05:35:45
Single Molecule Electron Crystallographyis better than 2 Angstrom which is sufficient for the recognition of the amino-acid residues of a polypeptide chain. With the electron microscope being such an ideal instrument for the elucidation of protein structure, one would wonder why X-ray crystallography still exists.
hazard
发表于 2025-3-31 09:56:32
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