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Controlled Release: Benefits vs. Risks,lease formulations and devices have already reached the market place, and many others are currently undergoing premarketing trials. One might say that controlled release has transgressed from its infancy through its childhood, and it is rapidly maturing to occupy a vital position in many important i领带 发表于 2025-3-31 05:38:18
Experimental Approaches for Achieving Both Zero-Order and Modulated Controlled Release from Polymerrelease rates decrease with time. From a pharmaceutical standpoint, it would be desirable for, many such systems to display zero-order release kinetics. Furthermore, in some circumstances (e.g., insulin delivery in diabetics) it would be useful to be able to achieve increased dosages on demand. In t受伤 发表于 2025-3-31 13:01:56
Pharmacokinetic Modeling of Gentamicin Release from a Prosthetic Heart Valve,ease is the prolonged delivery of a drug to a particular body compartment or anatomical target site. This goal is accomplished by the application of a therapeutic drug delivery system designed to control both temporal and spatial aspects of drug disposition.Veneer 发表于 2025-3-31 14:19:31
Controlled Drug Release from Polymeric Matrices Involving Moving Boundaries,ing the undissolved core and the partially extracted region. In the case of an erodible or swellable polymer matrix, the release kinetics is further complicated by the presence of a second moving boundary, namely the eroding or swelling polymer front. The mathematical descriptions of such mass transchassis 发表于 2025-3-31 19:35:08
Anthracycline-DNA Complexes as Slow-Release Preparations in the Treatment of Acute Leukemia, successful programs for treatment of acute non-lymphoblastic leukemia (ANLL) in adults now cause remission in about 70–80% of previously untreated patients. But most patients relapse despite maintenance therapy given at certain intervals. The response rate is then much lower and most of these patie不可侵犯 发表于 2025-4-1 01:29:11
Biological Activities and Targeting of Soluble Macromolecules, applications. Macromolecules may form an important class of drugs, but their potential in that respect, with the exception of polypeptidic hormones, still has not been realized. This review deals with the similarities in pharmacodynamic phases (drug-receptor interactions) of small and large molecul