苦涩 发表于 2025-4-1 01:59:57

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幻影 发表于 2025-4-1 07:45:28

FAT10,ts proteins to proteasomal degradation. The covalent linkage of ubiquitin or other ubiquitin-like modifiers (ULM) to specific substrates is achieved by adjoining them to target proteins with an enzyme cascade using three enzymes: E1, E2 and E3. The first enzyme activates the ULM, the second enzyme s

Constrain 发表于 2025-4-1 12:44:04

https://doi.org/10.1007/978-1-4419-6676-6Conjugation; Deconjugation; Groettrup; Modifiers; Ubiquitin; enzymes; regulation

hemophilia 发表于 2025-4-1 16:17:43

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聪明 发表于 2025-4-1 21:04:07

Mineralogy and Elemental Composition,markably pleiotropic effects on cell function. These posttranslational modifications share a common mechanism comprised of three steps: an activating enzyme to couple ATP hydrolysis to formation of a high-energy intermediate at the carboxyl terminus of ubiquitin or the ubiquitin-like protein, a liga

altruism 发表于 2025-4-2 02:41:41

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跳脱衣舞的人 发表于 2025-4-2 03:54:34

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Carcinogenesis 发表于 2025-4-2 09:39:51

Chemical Composition of Source Waters,nzymes regulate cell biology by conjugating ubiquitin onto target proteins that are involved in a multitude of processes. In most cases this leads to degradation of the target, but in some cases CRL-dependent ubiquitination acts as a switch to activate or repress target function. The ubiquitin ligas
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查看完整版本: Titlebook: Conjugation and Deconjugation of Ubiquitin Family Modifiers; Marcus Groettrup Book 2010 Landes Bioscience and Springer Science+Business Me