为现场
发表于 2025-3-30 08:31:58
A Practical Guide for the Efficient Formulation and Calibration of Large, Energy- and Rule-Based Mod
憎恶
发表于 2025-3-30 15:16:06
Design Principles Underlying Robust Adaptation of Complex Biochemical Networksosable into just two types of network building-blocks—opposer modules and balancer modules. Here we present an overview of the design principles that characterize all RPA-capable network topologies through a detailed examination of a collection of simple examples. We also introduce a diagrammatic me
HEW
发表于 2025-3-30 16:44:18
Multi-Dimensional Analysis of Biochemical Network Dynamics Using pyDYVIPACal to the field of synthetic biology. In this chapter, we will present a practical guide to the multidimensional exploration, analysis, and visualization of network dynamics using pyDYVIPAC, which is a tool ideally suited to these purposes implemented in Python. The utility of pyDYVIPAC will be demo
泥土谦卑
发表于 2025-3-30 21:21:46
Integrating Multi-Omics Data to Construct Reliable Interconnected Models of Signaling, Gene Regulato regulatory and protein-protein interaction (PPI) links connecting signaling proteins or transcription factors or miRNAs to metabolic enzymes and their metabolites using network analysis and mathematical modeling. These cross-pathway links were shown to play important roles in metabolic reprogrammin
敲竹杠
发表于 2025-3-31 00:52:52
Efficient Quantification of Extrinsic Fluctuations via Stochastic Simulations estimate these extrinsic fluctuations for experimentally constructed bidirectional transcriptional reporter systems along with the intrinsic variability. We use the Nanog transcriptional regulatory network and its variants to illustrate our numerical method. Our method reconciled experimental obser
biopsy
发表于 2025-3-31 07:03:48
Meta-Dynamic Network Modelling for Biochemical Networkseals the range of possible protein dynamics for a given network topology. Since MDN modelling is integrated with traditional ODE modelling, it can also be used to investigate the underlying causal mechanics. This technique is particularly suited to the investigation of network behaviors in systems t
注视
发表于 2025-3-31 10:55:48
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MIME
发表于 2025-3-31 14:52:26
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个阿姨勾引你
发表于 2025-3-31 18:04:44
Resolving Crosstalk Between Signaling Pathways Using Mathematical Modeling and Time-Resolved Singleof p53 to genotoxic stress using time-resolved single cell data and perturbed NF-κB signaling by inhibiting the kinase IKK2. Employing a subpopulation-based modeling approach enabled us to identify multiple interaction points that are simultaneously affected by perturbation of NF-κB signaling. Henc