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Historic Shipwreck Preserves in Marylandeld, resulting in a novel and exciting strategy called drug repurposing. Drug repurposing consists in finding new applications for existing drugs. Numerous computational methods perform a high-level integration of different knowledge sources to facilitate the discovery of unknown mechanisms. In thisServile 发表于 2025-3-29 00:32:45
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Historic Shipwreck Preserves in Maryland therapeutic purposes. Detection methods span a number of platforms, including cytogenetics (e.g., FISH), targeted qPCR, and sequencing-based assays. Before the advent of next-generation sequencing (NGS), fusion testing was primarily targeted to specific genome loci, with assays tailored for previou核心 发表于 2025-3-29 08:02:47
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https://doi.org/10.1057/9781137296504llowing noninvasive and real-time detection of novel biomarkers for cancer screening and dynamic monitoring of disease development. Currently, the biggest challenge liquid biopsies face is the selection of the highest signal-bearing tissues (blood/urine or others) and components for diagnosis, being明确 发表于 2025-3-30 02:59:36
https://doi.org/10.1057/9781137296504tic and molecular profile. The rapid development of novel high-throughput omics technologies in recent years has led to the generation of massive amount of complex patient data, which in turn has prompted the development of novel computational infrastructures, platforms, and tools to store, retrieve灾祸 发表于 2025-3-30 07:33:18
https://doi.org/10.1057/9781137296504y decreasing costs and increasing throughput and resolution are paving the way for the adoption of single-cell technologies in clinical settings for personalized medicine applications. In this chapter, we review the state of the art of single-cell DNA and RNA sequencing technologies, the computation