ordain
发表于 2025-3-30 10:20:04
Molecular Dynamics Simulation of Lipid-Modified Signaling Proteinsteins will be provided, using RAS proteins as illustrative examples. Throughout the chapter, we highlight the main advantages and limitations of simulating RAS and related lipid-modified G-proteins in biomimetic membranes.
责任
发表于 2025-3-30 13:55:52
Poor Person’s pH Simulation of Membrane Proteinss of structure and function are provided using two case studies, namely those of bioenergetic complexes: NADH dehydrogenase (complex I) and V. domain of V-type ATPase. The hybrid MCCE-MD pipeline has allowed the discovery of hydrogen bond networks, ligand binding pathways, and disease-causing mutations.