attenuate 发表于 2025-3-23 12:14:21
Sequence Analysis of Chromatin Immunoprecipitation Data for Transcription Factors,f the sequences of the identified regions allows binding to be localized at a higher resolution than can be achieved by current high-throughput experiments without sequence analysis and may provide important insight into the regulatory programs enacted by the protein of interest. In this chapter weDysarthria 发表于 2025-3-23 16:09:30
,Inferring Protein–DNA Interaction Parameters from SELEX Experiments,f oligonucleotides, of the oligomers with a high binding affinity for a given molecular target. The highest affinity binding sequences isolated through SELEX can have numerous research, diagnostic, and therapeutic applications. Recently, important new modifications of the SELEX protocol have been prlabyrinth 发表于 2025-3-23 22:01:16
http://reply.papertrans.cn/24/2322/232135/232135_13.pngPALMY 发表于 2025-3-23 23:30:26
http://reply.papertrans.cn/24/2322/232135/232135_14.pnganalogous 发表于 2025-3-24 04:29:09
http://reply.papertrans.cn/24/2322/232135/232135_15.png毗邻 发表于 2025-3-24 09:27:09
Computing Chromosome Conformation,n vivo. 3C studies indicate that genomes are likely organized into dynamic networks of physical contacts between genes and regulatory DNA elements. These interactions are mediated by proteins and are important for the regulation of genes. For these reasons, mapping physical connectivity networks witblackout 发表于 2025-3-24 14:29:30
http://reply.papertrans.cn/24/2322/232135/232135_17.png一夫一妻制 发表于 2025-3-24 16:17:22
Evolution of ,-Regulatory Sequences in ,,r, we review probabilistic models of evolution of transcription factor binding sites, which provide the theoretical basis for a number of new bioinformatics tools for comparative sequence analysis. We illustrate how important functional and evolutionary insights on binding site gain and loss can be茁壮成长 发表于 2025-3-24 20:18:42
http://reply.papertrans.cn/24/2322/232135/232135_19.png相符 发表于 2025-3-25 00:15:37
http://reply.papertrans.cn/24/2322/232135/232135_20.png