aesthetician
发表于 2025-3-30 09:23:06
John R. Gilbert,Hjálmtýr Hafsteinssone various processes of renal excretion and age. There is no doubt that the impairment of the renal excretion of drugs at the two extremes of age has therapeutic and toxicological implications (Morselli, 1976; Kampmann & Molholm Hansen, 1979; Schmucker, 1979). My purpose is not to present original re
CLEFT
发表于 2025-3-30 13:42:58
John R. Gilbert,Hjálmtýr Hafsteinsson adequate blood samples. As a result there is a relative abundance of pharmacokinetic studies in the elderly. However, even in infants and children increasingly complex pharmacokinetic studies can be attempted as more sophisticated methodology allows the use of small samples of blood.
pessimism
发表于 2025-3-30 17:09:47
https://doi.org/10.1007/978-1-4899-6048-1measuring those pharmacological effects were available such measurements might yield more useful information than the measurement of plasma drug concentrations, in terms of the final outcome. This notion is illustrated for the case of the cardiac glycosides (for example, digoxin) in Figure 1.
图画文字
发表于 2025-3-31 00:33:11
https://doi.org/10.1007/978-1-4899-6048-1 basis for desensitization it might be possible to design therapeutic strategies to alter it. However, since only agonists desensitize tissues (antagonists do not), it seems likely that the activating and desensitizing properties of various agonists are very intimately linked. Thus, a very detailed