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发表于 2025-4-1 03:25:53
The renal toxicity of beta-lactam antibiotics: Mechanisms and clinical implicationsmbered lactam ring, a nitrogen shared by the lactam and contiguous rings, and a carboxyl on the non-lactam ring removed by one carbon from the shared nitrogen. This central core, variably influenced by a series of side-group substituents, is important to the antibacterial action , renal tubular s
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发表于 2025-4-1 06:12:29
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发表于 2025-4-1 11:24:44
Miscellaneous drugs with nephrotoxic potential (Sulfonamides, sulfadiazine, trimethoprim-sulfamethox used extensively in the past for the treatment of general infections (sulfonamides), others have had specific indications (pentamidine, dapsone), and others such as quinolones are of more recent application. Many of these, however, have become currently important because of their use in the various