ornithology
发表于 2025-3-28 15:26:48
Minimal Residual Disease in Acute Lymphoblastic Leukemia: Techniques and Application Post-treatment MRD measured by sensitive methods, including multiparametric flow cytometry and real-time quantitative polymerase chain reaction (RQ-PCR), has been incorporated into clinical risk assignment, resulting in substantially improved outcomes. In addition, a novel molecular method, high-th
JADED
发表于 2025-3-28 22:48:33
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jocular
发表于 2025-3-28 22:59:36
Treatment of Adult B- and T-Cell Acute Lymphoblastic Leukemia: An Overview of Current Treatments andet al., J Clin Oncol, 2012). Conversely, ALL is a challenging disease to treat in adults and has a modest prognosis (Jabbour et al., Cancer, 2015). The treatment paradigm for adult ALL adapted from pediatric regimens comprises combination chemotherapy with cycles of induction, consolidation, mainten
d-limonene
发表于 2025-3-29 03:50:59
Acute Lymphoblastic Leukemia in Infants: A Distinctive, High-Risk Subtype of Childhood Acute Lymphobgene (.-r) on chromosome band 11q23 is a defining cytogenetic feature that occurs in approximately 80% of infants with ALL and is associated with poor prognosis for long-term remission and survival. Infant ALL with .-r is characteristically poorly responsive to chemotherapy and hematopoietic stem ce
做作
发表于 2025-3-29 10:33:48
Treatment of Elderly Patients with Acute Lymphoblastic Leukemia In sharp contrast, intensive pediatric chemotherapy regimens for children and adolescents/young adults (AYAs) achieve long-term disease-free remission rates of 80–90% and 50–70%, respectively. The poor prognosis of older adults with ALL is due to a high incidence of poor prognostic chromosomal and
同时发生
发表于 2025-3-29 12:56:51
Treatment of Childhood Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia been associated with poor outcome. The introduction of tyrosine kinase inhibitors targeting the BCR-ABL1 fusion protein to multiagent chemotherapy regimens has transformed the standard-of-care treatment approach for pediatric patients with Ph+ ALL, resulting in fewer patients being allocated to all
Biguanides
发表于 2025-3-29 19:03:30
Treatment of Adult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia were confronted with a dismal prognosis, they can now expect an outcome similar – or even superior – to other subtypes of ALL. Importantly, these improvements in survival were brought about by an integrated approach in which introduction of TKI early in the therapeutic regimen was complemented by d
影响带来
发表于 2025-3-29 21:59:58
Treatment of Ph-Like Acute Lymphoblastic Leukemiaith high relapse risk and inferior clinical outcomes. Ph-like ALL was first recognized as having a kinase-activated gene expression profile (GEP) similar to that of Philadelphia chromosome-positive ALL (Ph+ ALL) and frequent . (.) alterations, yet lacking the canonical . oncogene fusion. Advances in
圆木可阻碍
发表于 2025-3-30 02:59:06
Prophylaxis and Treatment of Central Nervous System (CNS) Acute Lymphoblastic Leukemiart to the discovery of the central nervous system (CNS) as a sanctuary site for leukemic blasts and implementation of CNS-directed therapy. With the application of risk-stratified, effective, systemic chemotherapy and prophylactic or treatment dosed CNS-directed interventions including intrathecal c
行为
发表于 2025-3-30 05:32:53
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