prodrome 发表于 2025-3-28 17:50:57
A Retrospective: On Disproving the Transcription–Translation Feedback Loop Model in Cyanobacteria has defied this influential model and set a milestone in chronobiology with the establishment of the in vitro reconstituted oscillator system. As a researcher who had the good fortune to witness this turning point, I would like to review the process from a very personal perspective. I have been str彻底明白 发表于 2025-3-28 20:20:31
Mechanistic Aspects of the Cyanobacterial Circadian Clockvariety of mechanisms arose throughout the evolutionary tree as an adaptation to predictable daily swings in ambient light and temperature. In this chapter we will focus exclusively on the circadian clock shared by the cyanobacteria . and ., with a noncomprehensive scope that emphasizes mechanism. Alanguor 发表于 2025-3-29 00:28:59
Mechanism of the Cyanobacterial Circadian Clock Protein KaiC to Measure 24 HoursiC shows a circadian rhythm. The major component KaiC is a typical adenosine triphosphatase (ATPase). Although ATPase activity of KaiC is extremely low, the ATPase activity of KaiC by itself shows temperature compensation and correlates with the rate of circadian rhythm (oscillation frequency), indi苦恼 发表于 2025-3-29 05:57:27
Oscillation and Input Compensation in the Cyanobacterial Kai Proteinshe phenomenology of this system with a focus on how the Kai oscillator is special compared to generic biochemical oscillators. A key feature is that many external perturbations couple much more strongly to the amplitude than to the period of oscillations. This property is the basis of the ability of傲慢物 发表于 2025-3-29 11:08:04
http://reply.papertrans.cn/23/2266/226577/226577_45.pngFRET 发表于 2025-3-29 13:44:11
http://reply.papertrans.cn/23/2266/226577/226577_46.pngingrate 发表于 2025-3-29 18:09:01
http://reply.papertrans.cn/23/2266/226577/226577_47.pngImmunoglobulin 发表于 2025-3-29 22:37:43
http://reply.papertrans.cn/23/2266/226577/226577_48.png善变 发表于 2025-3-30 01:32:03
An In Vitro Approach to Elucidating Clock-Modulating Metabolites turned out to be affected by metabolites that reflect photosynthetic activity. Reconstituting the bacterial timekeeper in a test tube containing only KaiA, KaiB, KaiC, ATP, and magnesium enabled a detailed functional analysis of the circadian clock. Here we added CikA, which competes with KaiA fordowagers-hump 发表于 2025-3-30 04:50:44
Damped Oscillation in the Cyanobacterial Clock Systemrial circadian system. First, low temperature transformed the self-sustained KaiC phosphorylation rhythm into damped oscillations. Second, deletion of the . gene showed damped oscillation in the bioluminescent rhythm. These damped rhythms resonated with periodical environmental changes and then reco