OGLE 发表于 2025-3-23 12:52:04
Thomas Reid,Ludwig Wittgensteinderstanding this organization requires the integration of many data types and experimental results. Here we describe the approach of integrating genome-wide protein–DNA binding data to determine chromatin states. To investigate spatial aspects of genome organization, we present a detailed descriptio开始从未 发表于 2025-3-23 15:41:50
http://reply.papertrans.cn/23/2264/226341/226341_12.pngwreathe 发表于 2025-3-23 21:23:46
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https://doi.org/10.1007/978-3-663-12339-2cells and by detecting cell-scattered light their number and relative size can be measured as they pass through the beam. Labeling of molecules, usually via a fluorescent reporter, allows the amount of these molecules per cell to be quantified. DNA content can be estimated using this approach and he沉默 发表于 2025-3-24 06:25:56
Studies in Computational Intelligencets during the cell cycle, for example, to reliably segregate daughter chromosomes. More recently, various labs have begun investigating the short-time dynamics (displacements during time intervals of 0.1–100 s), which one hopes to link to structure, in analogy to “microrheology” approaches applied s惊呼 发表于 2025-3-24 08:12:56
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Jeremy Grech,Mark Bugeja,Dylan Seychellrepair are driven by the mechanisms by which a functional nuclear protein finds its substrate in the nucleus. Single-particle tracking (SPT) is a method to quantify fluorescent molecules dynamics from the tracks of the single molecules recorded by high-resolution microscopes. SPT offers direct obser