RAFF
发表于 2025-3-23 12:50:20
P. Suchomel,O. Choutka,P. Barsalls in a population may contribute to survival and disease, most assays of chromatin structure recover only population averages. We have developed DNA methyltransferases (MTases) as probing agents of DNA accessibility in chromatin, either expressed in vivo in budding yeast or as recombinant enzymati
biosphere
发表于 2025-3-23 15:27:37
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entice
发表于 2025-3-23 21:30:16
https://doi.org/10.1007/978-3-642-13158-5enomic methylation of cytosines within CpG dinucleotides is crucial to development, gene silencing, and chromosome inactivation. Importantly, aberrant methylation profiles of various genes are associated with cancer as well as autoimmune disease, psychiatric and neurodegenerative disorders, diabetes
debacle
发表于 2025-3-24 01:50:13
Urban Forests Prior to World War II,12; Zentner and Henikoff, Nat Struct Mol Biol 20:259–266, 2013). One example of such modifications is histone ubiquitination, which occurs predominately on H2A and H2B. Recent studies have highlighted important regulatory roles of H2A ubiquitination in Polycomb group protein-mediated gene silencing
慢跑鞋
发表于 2025-3-24 04:09:50
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租约
发表于 2025-3-24 09:31:28
https://doi.org/10.1007/978-94-007-4396-0e is composed of core histones and DNA of variable size wrapped around it. Apart from the histone proteins, several nonhistone proteins also interact with the complex consisting of the DNA, the core and linker histones conferring highly regulated fluidity on the chromatin and permitting fine tuning
Blatant
发表于 2025-3-24 11:04:20
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预防注射
发表于 2025-3-24 17:43:57
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EXALT
发表于 2025-3-24 20:53:44
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FADE
发表于 2025-3-24 23:45:56
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