PAC
发表于 2025-3-30 10:54:00
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confederacy
发表于 2025-3-30 15:28:13
https://doi.org/10.1007/978-3-540-33310-4n) and fluorochromes used for the detection of cellular drug efflux and resistance (e.g., rhodamine 123, Hoechst 33342). Multi parametric flow cytometry can be used for identification of tumor cell subpopulations based on their drug retention profiles with or without the presence of an efflux blocke
Brocas-Area
发表于 2025-3-30 16:37:19
Björn Rasch,Malte Friese,Ewald Naumann blood and bone marrow cells. We describe a functional assay for P-glycoprotein using rhodamine 123, an assay for daunorubicin accumulation, and an assay to measure P-glycoprotein levels using the MRK16 antibody. Our protocols include the use of an anti-CD45 antibody for the identification of leukem
eustachian-tube
发表于 2025-3-30 20:51:12
https://doi.org/10.1007/978-3-540-33310-4iosides, and sphingosine. Ceramide production is increased in response to stress and toxic agents. Because modulation of ceramide levels has been shown to affect sensitivity and/or resistance to therapeutic agents, it will be important to assess the activity of sphingolipid metabolic pathways when i
Deference
发表于 2025-3-31 04:02:09
Björn Rasch,Malte Friese,Ewald Naumannotocol includes steps for drug exposure, RNA isolation, preparation of fluorescently labeled samples, microarray hybridization, data pro cessing, and data analysis. In addition to the detailed protocol, important experimental design issues are discussed, and some preliminary experiments are recommen
Manifest
发表于 2025-3-31 07:20:38
Springer Series in Chemical Physics the same mechanism, a supervised machine learning approach called support vector machine (SVM) is used to associate genes with any of five predefined anticancer drug mechanistic categories. The drug activity profiles are used as training examples to train the SVM and then the gene expression profil
GROUP
发表于 2025-3-31 09:50:32
Springer Series in Chemical Physicsmodel systems for the identification of determinants of chemosensitivity. Indeed, yeast mutants of DNA repair and cell cycle checkpoint pathways exhibit increased sensitivity to selected antitumor drugs, thereby allowing us to establish the role of specific genes in drug response. The basic cellular
habitat
发表于 2025-3-31 16:43:22
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