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Multifactor Interaction Network of Carcinogenesis — A “Tour Guide”. The multiplicity of these factors outdates the classical concept that a given carcinogen is the sole etiological agent in the “causation of a cancer”, except when under controlled laboratory conditions or resulting from well-defined occupational or lifestyle exposures. In the same framework the siGREG 发表于 2025-3-24 06:44:51
Synergism and Antagonism Between Chemical Carcinogenschemical carcinogens, which act either sequentially or simultaneously. This complex scenario has not adequately been modeled by routine testing for carcinogenicity in which relatively high doses of single agents have been used predominantly to establish the relative risk that chemical compounds mayInterferons 发表于 2025-3-24 12:53:52
Synergism in Carcinogenesis: Mathematical Approaches to its Evaluation are linear, then the two carcinogens would be in synergism if the tumor yield, when they are administered ., exceeded that obtained by the summation of the tumor yields from the separate testing of the two carcinogens at their respective single doses. For synergism to be established, the difference殖民地 发表于 2025-3-24 15:03:53
Inhibition of Chemical Carcinogenesis (1,2). Among the chemicals tested, representatives of numerous structural and biological activity classes have been found to be inhibitors. Examples of structural classes of inhibitors are arylalkyl isothiocyanates, cinnamyl compounds, flavonoids, glucarates, indoles, polyphenols, retinoids and carBUST 发表于 2025-3-24 21:55:17
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