邪恶的你 发表于 2025-3-30 10:39:57
Species-Dependent Differences in the Metabolic Activation of Polycyclic Aromatic Hydrocarbons in Cel that their production can be quantitated, it is possible to measure their formation through detection of the DNA adducts they produce. The DNA serves as both a critical target for the “ultimate carcinogenic metabolites” and as a nucleophilic trapping agent for detection and measurement of these reactive electrophiles.可卡 发表于 2025-3-30 13:43:22
Designing Encapsulated Class Typesthan normal HSF.. Aryl hydrocarbon hydroxylase (AHH) activities are lower in G6PD-deficient cells, when tested in the absence of exogenous NADPH.. G6PD-deficient cells, incubated . with BaP, produce low amounts of organic- and water-soluble BaP metabolites and show a decreased ability to form BaP-7,8-diol-9,10-epoxide and BaP-DNA adducts..商店街 发表于 2025-3-30 20:36:48
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http://reply.papertrans.cn/23/2243/224295/224295_55.pngabduction 发表于 2025-3-31 05:53:50
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Complex Metabolic Activation Pathways of Polycyclic Aromatic Hydrocarbons: 3-Hydroxy-trans-7,8-Dihydnd to DNA. and are mutagenic.. However, the active species have not yet been identified. Administration of 3-OH-BP to rats results in the excretion of sulfate and glucuronic acid conjugates of 3-hydroxy-.-7,8-dihydroxy-7,8-dihydrobenzopyrene (3-OH-BP-7,8-diol) (Fig. 1) as major metabolites in the朦胧 发表于 2025-3-31 23:19:42
Relationship Between Structure and Mutagenic/Carcinogenic Activity of Short Chain Aliphatic Halocompal and toxicological activity and, hence most important, potential population risk. They are probably the most ubiquitous in occurrence. A number of these, because of their use as pesticides and aerosol propellents and their high chemical stabilities, have become distributed throughout the biosphere