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Mechanisms of Neuroprotective Cytokinesinduced perforations in the blood-brain barrier (BBB) permit entry of humoral inflammatory mediators such as neutrophils and macrophages (Clark et al., 1994; Barone et al., 1992), whereas inherent CNS-resident microglial cells are activated following ischemic injury (Kim et al., 1995). These cells tmetropolitan 发表于 2025-3-29 06:50:39
Reprogramming of Gene Expression After Ischemiah responses in brain differ considerably after global and focal ischemia and are strongly dependent on the duration and severity of blood flow deficits. This review initially focuses on inducible transcription factors encoded by cellular immediate-early genes (cIEGs) of the . multigene families, andSHRIK 发表于 2025-3-29 09:24:22
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