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Neutrophils and Eosinophils in IgE-Dependent Allergic Tissue Reactions,uding neutrophils and eosinophils. Experimentally, it can be shown that following the interaction of specific antigen with mast cell-bound IgE (or equivalent homocytotropic antibody such as guinea pig IgG. or rat IgG.) a mechanism is inititated which results in the local accumulation of various cell