Criteria 发表于 2025-3-28 16:29:35
The Elephant in the Room: The Role of Microtubules in Cancer,s cellular motility, cytoplasmic transport and cell division. Some the most effective chemotherapeutics, such as the taxanes, are microtubule interfering drugs. Moreover, many studies suggest that microtubule dynamics are altered in cancer cell divisions and linked to chromosomal instability, aneuplchuckle 发表于 2025-3-28 21:16:32
Clinical Development of Anti-mitotic Drugs in Cancer,get for anticancer therapies since fast proliferation was identified as one of the hallmarks of cancer cells. Despite efforts into developing specific inhibitors for mitotic kinases and kinesins, very few drugs have shown the efficiency of microtubule targeting-agents in cancer cells with paclitaxelpineal-gland 发表于 2025-3-28 23:48:04
http://reply.papertrans.cn/23/2229/222807/222807_43.pngThyroiditis 发表于 2025-3-29 03:09:41
Unbalanced Growth, Senescence and Aging,icient cell material is available and affects the overall rate of cell proliferation. At a very fundamental level, cellular replicative lifespan—defined as the number of times a cell can divide, is a manifestation of cell cycle control. Hence, control of mitotic cell divisions, especially when the cartifice 发表于 2025-3-29 09:05:49
http://reply.papertrans.cn/23/2229/222807/222807_45.pngdebble 发表于 2025-3-29 12:43:57
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