歪曲道理
发表于 2025-3-23 11:07:29
http://reply.papertrans.cn/23/2228/222788/222788_11.png
儿童
发表于 2025-3-23 17:53:41
https://doi.org/10.1007/978-94-024-2115-6ical progression from normal cells to premalignant stages to invasive tumors. The multistep process in tumorigenesis is responsible for the age-dependent appearance of tumors in humans; four to seven major genetic alterations that accumulate over time are responsible for the development of the ultimate tumor cell.
Oligarchy
发表于 2025-3-23 18:32:57
http://reply.papertrans.cn/23/2228/222788/222788_13.png
MUT
发表于 2025-3-24 01:02:19
Cell Cycle Regulators,ical progression from normal cells to premalignant stages to invasive tumors. The multistep process in tumorigenesis is responsible for the age-dependent appearance of tumors in humans; four to seven major genetic alterations that accumulate over time are responsible for the development of the ultimate tumor cell.
Preserve
发表于 2025-3-24 05:23:12
Mammalian CDK Inhibitors as Targets of Ubiquitinization in Cancer, oscillate, being regulated mainly at the transcriptional level but also by protein degradation via the ubiquitin proteasome pathway (.). The activity of cyclin/CDK complexes is further regulated by both positive and negative phosphorylation events (.), as well as their association with specific inhibitory proteins (.).
Cholesterol
发表于 2025-3-24 08:57:55
2196-9906 rmation about the molecular biology of cell cycle control and demonstrate its clinical relevance to understanding neoplastic diseases. Topics range from Cdk inhibitors and cell cycle regulators to the prognostic value of p27 and tumor suppressor genes as diagnostic tools. Actual case studies show ho
semiskilled
发表于 2025-3-24 14:39:53
Maria Teresa Riviello,Anna Espositoordinated to occur in an ordered fashion at precisely the right time (for a review . refs. .). This regulation and coordination results from a combination of several signals from different regulatory pathways that are activated in response to the presence of specific stimuli (for a review . ref. .).
惊惶
发表于 2025-3-24 15:11:21
http://reply.papertrans.cn/23/2228/222788/222788_18.png
袋鼠
发表于 2025-3-24 22:03:37
http://reply.papertrans.cn/23/2228/222788/222788_19.png
珐琅
发表于 2025-3-25 02:27:50
Cell Cycle Regulators as Targets of Anticancer Therapy,nd mitosis: from growth factors to cyclin-dependent kinases. Given the increasing number of experimental therapeutic compounds, I will limit the discussion to those therapeutic agents that are undergoing at least Phase I clinical evaluation.