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Remote Control of Mammalian Therapeutic Designer Cellsar of medicine. Controlling and fine-tuning the behaviour of engineered cells is therefore becoming increasingly important. In the quest for the best-in-class genetic control modalities, traceless physical cues such as light, temperature, mechanical force, magnetic fields, and electrical pulses have自然环境 发表于 2025-3-22 00:24:20
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Monoclonal Antibody Glycoengineering for Biopharmaceutical Quality Assurancecribed for the treatment of several types of cancer and autoimmune disorders. Glycosylation is considered a critical quality attribute of mAbs because it is essential to the safety, pharmacokinetics, and pharmacodynamics of these life-saving biopharmaceuticals. High degrees of glycosylation variabil手段 发表于 2025-3-22 18:35:38
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Manufacturing Human Pluripotent Stem Cells and Differentiated Progenitorsdies have thus far demonstrated the maintenance of cells in static culture plates, which are difficult to scale-up to industrial manufacturing due to the vast quantities of cells required for therapy. Bioreactors have become the most promising alternative for large-scale production and studies haveFillet,Filet 发表于 2025-3-23 04:25:08
Biomanufacturing of Mesenchymal Stromal Cells for Therapeutic Applicationsed by degenerative diseases, or indirectly through secretion of trophic or immunomodulatory factors. However, it is estimated that 10.–10. MSCs are needed for a single dose. This, combined with the fact that MSC populations are heterogenous, presents a number of manufacturing challenges. Selection onepotism 发表于 2025-3-23 05:58:23
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