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https://doi.org/10.1007/978-94-010-3514-9tro studies of isolated type I collagen and procollagen have indicated that much of the assembly process of a collagen fibril can be explained by physicochemical forces, often described as “self-assembly.” Light microscopic studies of type I collagen-rich tissues reveal a variety of architectures ra屈尊 发表于 2025-3-22 11:50:12
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Introductory Remarksontinues to interact with its own ECM products, and with the ECM produced by other cells. At the cell surface, matrix receptors link the ECM to the cell interior; the metabolism and fate of the cell, its shape, and many of its other properties are continuously related to and dependent on the composi得罪 发表于 2025-3-22 17:31:28
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Proteoglycanseeks, and cell surface PGs generally have half-lives of only a few hours. Changes in the metabolism and structure of PGs can have profound effects on the pathobiology of many diseases. This chapter, then, summarizes current concepts and problems relating to biosynthesis, catabolism, and pathology ofCytology 发表于 2025-3-23 03:32:54
Matrix Assemblytro studies of isolated type I collagen and procollagen have indicated that much of the assembly process of a collagen fibril can be explained by physicochemical forces, often described as “self-assembly.” Light microscopic studies of type I collagen-rich tissues reveal a variety of architectures ra勉强 发表于 2025-3-23 07:45:22
Extracellular Matrix Degradationo cell migration. In contrast to the involution reaction, lysis associated with cell motility is a limited reaction that leaves the bulk of the matrix intact and is directed only at the “structural kingpins,” those molecules that constitute a barrier to cell displacement. Cell growth, division, and