剧本
发表于 2025-3-27 00:30:39
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遣返回国
发表于 2025-3-27 01:13:37
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CRASS
发表于 2025-3-27 08:11:12
Design and Conduct of the Thorough Phase I ECG Trial for New Bioactive Drugschemical structures. Some examples include the antihistamine terfenadine; the antibiotic grepafloxacin; the antispasmodic terodiline; the calcium channel blocker lidoflazine; the atypical antipsychotic sertindole; the opioid levomethadyl; and the gastric prokinetic agent cisapride.
绊住
发表于 2025-3-27 11:56:38
Use of ECGs in Support of Cardiac Safety in Phase II and III Clinical Trials a drug’s potential to cause TdP. This chapter will focus on the use of standard 12-lead ECGs in phases II and III clinical development to assess a drug’s effect on cardiac intervals, durations, and morphologic patterns.
抛媚眼
发表于 2025-3-27 17:08:57
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obscurity
发表于 2025-3-27 18:58:32
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CURL
发表于 2025-3-27 23:28:29
Cellular, Molecular, and Pharmacologic Mechanisms Underlying Drug-Induced Cardiac Arrhythmogenesisivity in the form of early or delayed afterdepolarizations. Modulation of ion channel activity by drugs contributes to the development of both passive and active cardiac arrhythmias. The mechanisms responsible for active cardiac arrhythmias are generally divided into two major categories: (1) enhanc
试验
发表于 2025-3-28 04:36:36
hERG Assay, QT Liability, and Sudden Cardiac Deathar) (.) have been associated with prolongation of the QT interval of the electrocardiogram (ECG), polymorphic ventricular tachycardia, torsades de pointes (TdP), and sudden cardiac death. Regulatory agencies such as the Food and Drug Administration (FDA) responded initially with severe labeling rest
Incisor
发表于 2025-3-28 10:05:24
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诱骗
发表于 2025-3-28 11:06:34
Assessment of Ventricular Repolarization From Body-Surface ECGs in Humanss called A, B, C, and D. Einthoven mathematically modified this signal to correct the inertia associated with the movement of the mercury column in the capillary electrometer. To avoid confusion with Waller’s recording, Einthoven named the five identified deflections P, Q, R, S, and T having used th