ETHER 发表于 2025-3-28 17:55:17
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Business Cycles: Discrete Time,dihydroxybenzo(a)pyrene and 9-hydroxybenzo(a)pyrene are the major DNA-binding species formed in different experimental systems. Both the extent and pattern of formation of DNA-bound benzo(a)pyrene metabolites varies however between different systems. The formation of DNA-bound metabolites of 9-hydro火花 发表于 2025-3-29 06:33:31
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Business Cycles: Continuous Space,mum conditions, a binding level of one AFB., residue per 18 DNA nucleotides can be attained. Acid hydrolysis of the modified DNA liberates a mixture of adducts, of which the major one, representing about 90% of bound AFB., is 2,3-dihydro-2-(N.-guanyl) -3-hydroxyAFB. (I). A single i.p. injection of AGoblet-Cells 发表于 2025-3-29 12:17:55
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https://doi.org/10.1007/978-3-642-97291-1tNU), a highly potent mutagen and pulse-carcinogen (with a developmental stage-dependent, neural tissue-specific tumorigenic effect in rats), about a dozen different DNA ethylation products are known. Of the various sites of ethylation in DNA, the O.-position of deoxyguanosine (dGuo) is of particula营养 发表于 2025-3-29 22:20:58
https://doi.org/10.1007/978-3-642-97291-1 as previously defined in epidermal carcinogenesis in the mouse. Evidence is presented that the immediate clonal progeny of initiated hepatocytes can be distinguished as foci by one of four histochemical techniques. 85% of the total identifiable foci could be scored as .-glutamyl peptidase positivefigure 发表于 2025-3-30 02:42:14
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