围巾 发表于 2025-3-28 17:19:01
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Immunomodulation by Anticancer Drugs in Therapeutics,rge proportion of patients with the most common so-called solid tumors can be provided curative treatments. The limitations of chemotherapy are essentially related to the insufficient selectivity of antitumor activity of the drugs available and to the phenomenon of resistance. Intensive efforts areallergy 发表于 2025-3-29 01:46:20
Differential Effects of Low Doses Of Structurally Different Anthracyclines on Immunoglobulin Producuction of molecules that are usually synthesized by terminally-differentiated cells. For instance, anti-neoplastic drugs such as Ara-C or doxorubicin (DOX) promote the irreversible induction of hemoglobin (Hb) synthesis in human erythroleukemia K562 cells with a concomitant loss of proliferative capAnal-Canal 发表于 2025-3-29 04:12:02
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Reversal of Drug Resistance: Synergistic Anti-Tumor Cytotoxic Activity by Combination Treatment witre is relapse with the development of metastases and highly resistant tumor cells. A major challenge remains in the development of new therapeutic modalities that can treat widespread metastases and drug resistant tumors.Ardent 发表于 2025-3-29 15:03:59
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Effects of Tumor Necrosis Factor-Alpha on Growth and Doxorubicin Sensitivity of Multidrug Resistant effect as well as the possibility to favourably modulate tumor sensitivity to antineoplastic drugs (Alexander et al., 1987; Kikuchi et al., 1992; Wadler and Schwartz, 1990). However, information on their activity on chemoresistant tumors is still scanty (Billi et al., 1991; Bonavida et al., 1989; D争吵加 发表于 2025-3-29 22:42:30
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Synergic Interaction between Simvastatin and Antineoplastic Drugs on Glioma Cell Growth,d several non sterol products in animal cells (Goldstein, Brown, 1990). Inhibition of this enzyme triggers regulatory response that lowers the concentrations of low density lipoproteins (LDL) in blood. A major relationship exists between the cell growth processes and the mevalonate biosynthetic pathCongruous 发表于 2025-3-30 05:53:50
,CNS and Cardiovascular Effects of TNF-α,ical trials turned out to be impraticable because of severe systemic side-effects (Chouaib et al., 1992). The cardiovascular system and Central Nervous System (CNS) represent the main targets of Tumor Necrosis Factor (TNF-α) toxicity. Experimental studies have confirmed that systemic or intracerebra