WAG 发表于 2025-3-23 09:42:12
B7.1,id tumors (Lenschow et al. 1996). Nevertheless, B7-1 has been shown to be essential for the induction of T-cell responses, which play a central role in mediating tumor immunosurveillance and immune-mediated tumor regression (Ward and Kaufman 2007). B7-1 consequently plays an important role in cancertenosynovitis 发表于 2025-3-23 17:32:10
Bacterial Vaccines,rplay, as well as the recent advances in genetic engineering. Safe, targeted therapies are being developed, in which genetically-modified pathogens are designed to trigger effective anti-tumor immune response. Here we describe the bacterial strains intended for cancer immunotherapies, the genetic mo周年纪念日 发表于 2025-3-23 19:10:51
BH3-Only Mimetics,specific groove of anti-apoptotic Bcl-2 family survival factors in a similar manner to native proteins within the cell that regulate these factors. This primes the cell for apoptosis. Several small molecule BH3 mimetics are currently undergoing evaluation in clinical trials.壮丽的去 发表于 2025-3-23 22:58:45
http://reply.papertrans.cn/23/2213/221211/221211_14.pngCommonplace 发表于 2025-3-24 05:29:56
BRCA1 and 2,ion to breast cancer, and BRCA2 additionally predisposes to ovarian cancer. Women who carry high-risk BRCA1 mutant alleles have a 50–85 % chance of developing breast cancer by age 70 years. Differences in cancer risk estimates appear to be due to the extent of family history, with a strong family hitenosynovitis 发表于 2025-3-24 07:44:09
http://reply.papertrans.cn/23/2213/221211/221211_16.pngGRAIN 发表于 2025-3-24 11:43:44
CCL21, tumors of low immunogenicity. CCL21 mediates the recruitment and co-localization of naive lymphocytes and antigen-stimulated DC into T-cell zones of secondary lymphoid organs, facilitating T-cell activation. In this chapter, we discuss CCL21 as a novel agent to boost immune responses against cancer暂时中止 发表于 2025-3-24 16:09:27
CD4+ T Cells, cytokines and expression of distinct intracellular transcription factors and surface chemokine receptors. The functional diversity of T cells is demonstrated by the association of certain CD4+ T cell types (including Th1 CD4+ T cells) with positive cancer prognosis and other CD4+ T cell types (incl开头 发表于 2025-3-24 22:57:21
http://reply.papertrans.cn/23/2213/221211/221211_19.png倔强一点 发表于 2025-3-25 00:02:14
S. Roussos,C. R. Soccol,C. AugurUpon reactivation of AR-FL and expression of AR-Vs, traditional methods of treatment targeting the ligand binding domain are ineffective. Targeting the evolutionarily conserved N-terminal domain, DNA binding domain (DBD) or using transcription factors that interact with AR will be key in developing new treatments for PCa.