北极人 发表于 2025-3-26 21:36:35
http://reply.papertrans.cn/23/2212/221194/221194_31.pngJIBE 发表于 2025-3-27 01:48:52
,Epithelial–Mesenchymal Transition and Cancer Stem Cells,etastasis of cancer stem cells (CSCs). Several signal transduction mechanisms induce EMT, which causes the gene expression alteration to induce the acquisition of resistance and metastasis in cancer. EMT is characterized with high gene expression of cadherin 2 (N-cadherin) and vimentin, and sparse cdetach 发表于 2025-3-27 07:14:00
The Transcription Factors Zeb1 and Snail Induce Cell Malignancy and Cancer Stem Cell Phenotype in Pan extended period of prostate cancer, malignant cells are androgen-sensitive being testosterone the main responsible for tumor growth. Accordingly, treatments blocking production and action of testosterone are mostly used. However, during disease progression, PCa cells become androgen insensitive pabstemious 发表于 2025-3-27 12:00:43
ERBB Signaling Pathway in Cancer Stem Cells,hich consists of four type I transmembrane receptor tyrosine kinases, ERBB1, 2, 3 and 4. ERBBs form homo/heterodimers after ligand binding except ERBB2 and consequently becomes activated. Different signal pathways, such as phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT), RAS/RAF/MEK/ERK,祖先 发表于 2025-3-27 14:11:56
http://reply.papertrans.cn/23/2212/221194/221194_35.pngblithe 发表于 2025-3-27 18:30:31
http://reply.papertrans.cn/23/2212/221194/221194_36.pngambivalence 发表于 2025-3-27 23:12:07
http://reply.papertrans.cn/23/2212/221194/221194_37.pngFLASK 发表于 2025-3-28 03:22:09
http://reply.papertrans.cn/23/2212/221194/221194_38.pngOligarchy 发表于 2025-3-28 09:58:21
10楼PACT 发表于 2025-3-28 12:06:48
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