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Role of Cytokines in Tumor Immunity and Immune Tolerance to Cancer,une responses. While certain cytokines produced in the tumor microenvironment can inhibit tumor growth, others promote tumor growth and progression. Here, we review the roles of antitumor cytokines (IL-12 and IL-27) with potential preclinical and clinical applications, as well highlight pro-tumor cyNOVA 发表于 2025-3-24 00:53:47
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Endoplasmic Reticulum Stress and Autophagy in Cancer, of the ER homeostasis. Nutrient deprivation, hypoxia, and calcium depletion are some conditions which can compromise the homeostasis of this compartment. To overcome the imbalanced ER protein-folding capacity, cells have evolved an evolutionary conserved signal transduction pathway called unfoldedEuthyroid 发表于 2025-3-24 20:44:40
Prognostic Value of Innate and Adaptive Immunity in Cancers,y, how cancer cells progress and acquire their metastatic ability still remains debated. Tumors are heterogeneous cellular systems whose growth depends on dynamical interactions among the cancer cells, and between cells and the constantly changing microenvironment. Several types of immune cells, inc妈妈不开心 发表于 2025-3-25 02:28:02
https://doi.org/10.1007/978-3-319-54964-4stem can recognize tumor cells and mediate antigen-specific tumor rejection under certain condition. The molecular and cellular basis of immune recognition and antitumor immunity is now better understood. In addition, it is now evident that tumors may mediate immunosuppression through various solubl