Bumptious 发表于 2025-3-26 23:01:17
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K. Okumura,F. Viallefond,M. Viton,W. Rice. Advances in designing tumor-selective viral and nonviral vectors allow for more efficient gene delivery. Clinically approved gene therapies can be classified into several approaches such as sensitizing tumors to chemotherapies, targeting angiogenesis, and restoring tumor suppressing functions. AdjSpartan 发表于 2025-3-27 06:50:29
J.F. Bonaparte,C.L. Schultz,M.B. Soareshe treatment of solid tumors. Myeloablative, reduced-intensity, or non-myeloablative “conditioning” serves to eliminate or reduce the number of malignant cells, create “space” in the hematopoietic compartment for the expansion of transplanted hematopoietic cells, and provide a hematopoietic environmhegemony 发表于 2025-3-27 09:32:45
Sankar Chatterjee,Christopher Scoteset it offers a potential readily available family donor to almost every patient. The application of h-HCT has particularly benefited minority populations who frequently do not find a suitable unrelated donor. Different options exist utilizing either T cell depletion strategies or T cell-replete graftMEAN 发表于 2025-3-27 16:57:57
New Aspects of Mesozoic Biodiversityective immune response against cancer cells and to revert the immunosuppressive microenvironment are currently being carried out. Cytokines such as interleukin (IL)-2, IL-7, IL-12, IL-15, IL-18, granulocyte macrophage colony-stimulating factor (GM-CSF), granulocyte colony-stimulating factor (G-CSF),reception 发表于 2025-3-27 21:49:02
New Aspects of Mesozoic Biodiversitycle to infect a host cell. Besides viral interference, since their discovery, IFNs have been further implicated in different processes linked to immunity and cancer. The family of IFNs has been divided into three categories according to biological properties and signaling pathways: type I IFNs (consmonochromatic 发表于 2025-3-28 01:02:29
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https://doi.org/10.1007/978-3-322-99112-6em attractive targets for cancer immunotherapy, namely, their major histocompatibility complex (MHC)-unrestricted recognition of tumors, potent cytotoxicity, and abundant production of interferon-γ (IFN-γ) and tumor necrosis factor (TNF). Moreover, seminal work with mice genetically deficient for γδinculpate 发表于 2025-3-28 09:49:10
New Aspects of Nuclear Dynamicsreat majority of patients. During the past few decades, several strategies for enhancing its efficacy have been developed and introduced into the clinic. These include different maneuvers such as ex vivo expansion of autologous lymphocytes isolated from tumor, manipulating tumor-infiltrating lymphoc有效 发表于 2025-3-28 11:58:26
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