Essential 发表于 2025-3-28 15:41:13
P. P. Raj,D. D. Denson,R. H. De Jongthis is a common mechanism for tumours to evade CTL killing it is an important component of any immune response induced by a cancer vaccine. The potential of antibody responses to contribute to anti-tumour effects is less clear. The ‘type 1’ T cells that help in the activation of CTLs can help in thIge326 发表于 2025-3-28 21:17:35
Hans Joachim Wüst,M. d’Arcy Stanton-Hicks direct delivery of immunostimulatory molecule genes to tumours . also shows some efficacy, especially the suicide gene Herpes Simplex Virus thymidine kinase. Future clinical trials in earlier stage patients will provide the clearest indication of the efficacy of immunization with transduced tumour不法行为 发表于 2025-3-29 01:21:46
http://reply.papertrans.cn/23/2212/221127/221127_43.pngAnonymous 发表于 2025-3-29 03:33:01
Immunogenicity of tumour associated antigens, document that at least some (most?) types of cancer are antigenic. Within the past five years, the number of molecular and cellular immunological techniques for identifying tumour-associated antigens has increased to such extent that over 100 distinct genes have now been associated with the transfo剧毒 发表于 2025-3-29 09:30:18
Recognition of human tumours: cancer/testis antigens,]. The largest group is the group of cancer/testis (CT) antigens. Originally discovered in melanomas , they have been found in many human malignancies. Among normal tissues they are expressed in testes (therefore they have been designated cancer/testis antigens ) and in some cases in placenta,jumble 发表于 2025-3-29 11:40:14
Recognition of human tumors: SEREX expression cloning to identify tumour antigens,nology. The knowledge of their molecular nature provides us not only with potential targets for immunotherapeutic interventions against neoplastic cells, but also provides us with new disease markers and new insights into the molecular mechanisms of malignant transformation.恶意 发表于 2025-3-29 19:32:11
http://reply.papertrans.cn/23/2212/221127/221127_47.pngLeaven 发表于 2025-3-29 22:49:23
Carcinoembryonic Antigen as a Vaccine Target, provide an overview of the CEA gene family and the levels of expression of CEA in neoplastic and preneoplastic lesions, and in some normal and fetal tissues. The pros and cons of using animal models will then be discussed for (a) defming the optimal strategies for inducing an immune response and an喃喃诉苦 发表于 2025-3-30 00:58:53
http://reply.papertrans.cn/23/2212/221127/221127_49.pngFECT 发表于 2025-3-30 05:21:37
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