lexicographer 发表于 2025-3-21 18:38:31
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PI3K/AKT Pathway and the Epithelial-Mesenchymal Transitionhibitor .. By some estimates, . carries gain-of-function mutations in 32% of colorectal cancers, 36% of hepatocellular carcinomas, 36% of endometrial carcinomas, 25% of breast carcinomas, 15% of anaplastic oligodendrogliomas, and 5% of medulloblastomas and anaplastic astrocytomas (recently reviewedlinear 发表于 2025-3-22 01:03:35
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Myc and Control of Tumor Neovascularization control of a heavy chain gene enhancer (Dalla-Favera et al. 1982; Taub et al. 1982). Additionally, double minute chromosomes (dmin) containing amplified copies of the c-Myc gene are commonly detected in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) (Storlazzi et al. 2004). In parBarrister 发表于 2025-3-23 02:17:50
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Ink4a Locus: Beyond Cell Cycleactivation of p16 include melanoma, adenocarcinoma of the breast, squamous cell carcinomas of the lung, pancreatic adenocarcinomas, and colorectal carcinomas (Baylin et al. 1998; Pollack, Pearson, and Hayward 1996). In pancreatic adenocarcinoma, the frequency of p16 inactivation approaches 100% (Cal