humectant
发表于 2025-3-30 10:52:43
Simultaneous Mapping of Enhancers and Enhancer Rearrangements with Paired-End H3K27ac ChIP-seq, map enhancers and their activity and to identify structural variations at enhancers. Since changes in enhancer activity and new enhancer translocations both play a major role in tumor initiation, progression, and response to therapy, this approach holds promise to uncover some of the mechanisms behind these processes.
裂口
发表于 2025-3-30 14:32:22
Drug Target Prediction Using Context-Specific Metabolic Models Reconstructed from rFASTCORMICS,er but also to predict drug targets and candidate drugs for repurposing. Here, we will elaborate on the reconstruction of context-specific metabolic models of cancer using rFASTCORMICS and the subsequent prediction of drugs for repurposing using our drug prediction workflow.
ALE
发表于 2025-3-30 18:24:27
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无脊椎
发表于 2025-3-30 21:48:41
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自由职业者
发表于 2025-3-31 01:25:18
https://doi.org/10.1007/978-94-009-7043-4ically separate, yet chemically connect, two cell types; however, the majority of these approaches utilize batch culture conditions which can result in nutrient depletion and waste accumulation. This chapter describes an alternative approach that allows for the continuous infusion of media, relievin
Magnificent
发表于 2025-3-31 06:59:39
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阻碍
发表于 2025-3-31 12:25:00
Neutron Radiography at Lucas Heightss-all” therapeutic concept may commonly fail in terms of efficacy, evolving drug resistance, and side effects. In times of omics, novel elaborated and personalized approaches emerge for efficiently eradicate cancer cells, while sparing healthy cells. Synthetic lethality-based strategies offer promis
放肆的你
发表于 2025-3-31 13:54:12
https://doi.org/10.1007/978-94-009-8567-4lapsed disease hinders the development of novel therapeutics. 2D and 3D in vitro cell-based assays have provided some information, but this is limited and does not consider the role of the tumor microenvironment. The development of an in vivo assay can allow to generate resistance, while taking into