Defect 发表于 2025-3-21 17:49:01
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Peter F. Matthiessen,Peter Selgs Clustered Regularly Interspaced Short Palindromic Repeats or CRISPR. Advances in our understanding of their biological significance and potential applications for biotechnology have followed a two-phased development. Initial studies were few and mainly descriptive of arrays of interspaced repeats审问 发表于 2025-3-22 06:24:09
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,Körperorientierte Psychotherapie u.a.,ting fragments of alien genomes into specific genomic loci, transcribing the inserts and using the transcripts as guide RNAs to destroy the genome of the cognate virus or plasmid. This RNA interference-like immune response is mediated by numerous, highly diverse Cas (CRISPR-associated) proteins, sev仔细检查 发表于 2025-3-22 16:25:15
F.-E. Brock,H. Piazena,H. Mefferts phage and (conjugative) plasmids. However, under some conditions, cells may experience a selective advantage if they avoid energy investment in CRISPR defense, for example, if they contain additional defense systems (e.g., R-M systems, phage exclusion systems) that provide sufficient protection. T仔细检查 发表于 2025-3-22 20:30:45
,Körperorientierte Psychotherapie u.a.,de the Cas protein(s) to the cognate invading nucleic acids for their destruction. The biogenesis of mature crRNAs involves highly precise processing events. Interestingly, different types of CRISPR-Cas systems have evolved distinct crRNA maturation mechanisms. The CRISPR repeat-spacer array is tranCRUDE 发表于 2025-3-22 21:36:46
https://doi.org/10.1007/978-3-662-08913-2w includes an analysis of the distribution of CRISPR-Cas systems among the different bacterial and archaeal lineages, and will focus on our mechanistic understanding of the type I-E system of .. We will cover the overall organization of this system, starting with a detailed description of a typicalcollagenase 发表于 2025-3-23 02:53:46
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