无力更进 发表于 2025-3-26 23:39:32

Association of COX-2 and PPARs in Carcinogenesis and Chemopreventionreceptors in human malignancies, involvement of PPARs in tumorigenesis, and use of receptor antagonists or agonists for differentiation therapy and chemoprevention. It is proposed that PPARy agonists or PPARS antagonists may serve as more specific and less toxic agents for chemoprevention.

借喻 发表于 2025-3-27 03:02:59

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Parley 发表于 2025-3-27 09:00:46

Dietary Fatty Acids, COX-2 Blockade, and Carcinogenesispment of several human cancers. Specifically, polyunsaturated fatty acids such as linoleic acid (C18:2,n-6) and arachidonic acid (C20:4,n-6) enhance experimental carcinogenesis, tumor development, and tumor progression. In contrast, monounsaturated fatty acids such as oleic acid (C18:1, n-9) or poly

遭受 发表于 2025-3-27 09:44:45

Historical Aspects of COX-2 of polyunsaturated fatty acids (PUFAs) can serve as precursors to the eicosanoids, the bulk of the prostanoids and leukotrienes are derived from arachidonic acid (AA). Precursor AA does not exist free in cells; AA is present in membrane bound glycerophospholipids. When cells receive an appropriate

insincerity 发表于 2025-3-27 15:14:53

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不发音 发表于 2025-3-27 20:38:56

Epidemiology of Breast Cancer and Nonsteroidal Anti-Inflammatory Drugsagainst human disease. Aspirin, the prototype NSAID, is recommended for the chemoprevention of myocardial infarction (MI) and stroke .. Animal models of carcinogenesis provide strong evidence that NSAIDs inhibit tumor development in the colon and breast (., Chapters 5 and 6), and human epidemiologic

dissolution 发表于 2025-3-27 21:59:20

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Glutinous 发表于 2025-3-28 04:28:48

Chemoprevention of Breast Cancer by Nonsteroidal Anti-Inflammatory Drugs and Selective COX-2 Blockads and improved screening methods for early detection and treatment, breast cancer mortality has remained persistently constant for more than half a century. Novel preventive approaches are needed that deter or arrest mammary carcinogenesis .. A promising new lead for the control of this malignancy c

不足的东西 发表于 2025-3-28 08:59:51

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neutral-posture 发表于 2025-3-28 11:31:49

Nonsteroidal Anti-Inflammatory Drugs, Prostaglandins, and ,-Driven Intestinal Tumorigenesish respect to the genetic mutations that contribute to its development and progression to fatal malignancy .. Most cases of colorectal cancer occur spontaneously, but in some families germline mutations that affect either the adenomatous polyposis coli (.) gene or one of the mismatch DNA repair genes
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查看完整版本: Titlebook: COX-2 Blockade in Cancer Prevention and Therapy; Randall E. Harris Book 2003 Springer Science+Business Media New York 2003 Prevention of b