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Ray Taras (Professor in Political Science)Long DNA sequences are often heterogeneous in composition. Hidden Markov models are then good statistical tools to identify homogeneous regions of the sequences. We compare different identification algorithms for hidden Markov chains and present some applications to bacterial genomes to illustrate the method.conspicuous 发表于 2025-3-31 00:51:29
https://doi.org/10.1057/978-1-137-47630-2Since standard software does not incorporate the full spectrum of model search techniques, more sophisticated methods are not often used in practice. This paper aims to give a rundown of what is possible in this area and indicates some ideas for applications not previously thought of.