albuminuria 发表于 2025-3-26 23:22:24
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Experimental Brain Metastasisidler and Nicolson 1979; Nicolson 1978a). First, emergent malignant tumor cells must be able to survive and grow in a potentially hostile environment and proliferate to form a primary tumor. Once a primary tumor is established, invasion of surrounding normal tissues may take place by mechanical infi修剪过的树篱 发表于 2025-3-27 07:48:02
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Brain Tumor Microvasculatureumors induced by intracerebral inoculation of avian sarcoma virus (Brightman et al. 1971). We were impressed with the possible biologic and clinical significance of these defects and extended our findings to experimental gliomas in the dog (Vick and Bigner 1972b) and the rat (Yung et al. 1976). SubsLAIR 发表于 2025-3-28 00:04:27
A Model for Brain Metastasis 1977). None can be used directly to test for hematogenous metastatic disease because each depends on direct tumor (or viral) implantation into the brain, which necessarily traumatizes the brain. In order (1) to circumvent the problem of mechanical disruption of brain tissue so as to examine chemoth胎儿 发表于 2025-3-28 03:08:57
Pharmacokinetics and Metastatic Brain Tumor Chemotherapy view, focusing on the transport steps involved in drug delivery to the tumor cells and the major parameters which affect that delivery. Second, the parameters of drug administration which can be varied by the clinician to achieve optimal drug delivery and an optimal chemotherapeutic effect are discFacet-Joints 发表于 2025-3-28 09:37:56
Human Cancer Immunologygens on their surface. The evidence supporting this assumption comes primarily from transplantation experiments in inbred mice and rats with tumors induced by chemical carcinogens or viruses. The demonstration that these tumors are immunogenic in syngeneic hosts, or even in the host in which the tum有说服力 发表于 2025-3-28 12:21:10
Computed Tomography of Metastatic Disease of the Brain (CAT) by Hounsfield (1973) has revolutionized the diagnosis and management of cranial and intracranial metastatic disease. Since installation of a CT scanner at Memorial Sloan-Kettering Cancer Center in December 1975, approximately 9,500 patient examinations have been performed, 60% of which were e