construct 发表于 2025-3-26 20:59:37
Kininogenases of Blood Cells (Alternate Kinin Generating Systems),od disorder known as Williams Trait (. et al., 1977), kinin generation still occurs. This must be in part the result of the liberation of kinin from “alternate” kinin generation systems. Table 1 lists these alternate kinins generating systems which will now be described and compared to the kallikrein-kinin generating system of plasma.无法治愈 发表于 2025-3-27 01:37:34
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https://doi.org/10.1007/978-3-658-01154-3discovered that the incubation of trypsin or the snake venom of . with a pseudoglobulin fraction of plasma resulted in the formation of a potent vasodilator and smooth-muscle-stimulating substance. Because the guinea pig ileum responded slowly to the substance, compared with histamine or acetylcholihermetic 发表于 2025-3-27 10:21:56
https://doi.org/10.1007/978-3-322-95793-1ate amounts of bradykinin well over 1000 times its presumed normal baseline levels. Bradykinin has a half life of under 30 sec in plasma in vitro (. and ., 1970). In spite of these drawbacks, it has been possible to develop and use kinin radioimmunoassay to great advantage. Antibodies to bradykininGentry 发表于 2025-3-27 16:02:59
https://doi.org/10.1007/978-3-322-80523-2 pain is also evoked in man by intradermal and i.a. injections of bradykinin; i.p. administration causes pain most often described as cramping or colicky (. et al., 1967), although the pain was associated with sensations of pressure, distention, or burning in some subjects. The algesic effect of kin一致性 发表于 2025-3-27 18:16:54
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Book 1979 or modulate the actions of other agents, including prostaglandins, histamine, and catecholamines. Inhibitors of kallikrein or kininase II are employed, for example, in extracorporeal circulation or in hypertension. Kallikrein, kinins, and kininases, present in urine, were described first in 1925 anAnkylo- 发表于 2025-3-28 04:45:33
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