少量 发表于 2025-3-28 17:45:19
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Book 2008 carefully crafted sections introducing key concepts and advances in the areas of dissolution, BA/BE, BCS, IVIC, and product quality, with specific focus on integration of regulatory considerations and case histories highlighting the biopharmaceutics strategies adopted in development of successful drugs. .blight 发表于 2025-3-29 00:41:12
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Molecular and Physicochemical Properties Impacting OralAbsorptionofDrugs,ase of compliance, and cost-effectiveness. Not surprisingly, desirable oral bioavailability is one of the most important considerations for the successful development of bioactive molecules. Poor oral bioavailability affects drug performance and leads to high intra- and inter-patient variability.Foreshadow 发表于 2025-3-29 15:43:20
Dissolution Testing,ds has become one of the most important tests in drug product development and manufacturing, as well as in regulatory assessment of drug product quality. Not only can dissolution testing provide information regarding the rate and extent of drug absorption in the body, it can also assess the effectsBLA 发表于 2025-3-29 22:23:54
Drug Absorption Principles,the systemic circulation from the site of administration. Distribution of a drug includes all the processes that are involved from the time when the drug reaches the circulation to the time when it (or a metabolite of the drug) leaves the body. Metabolism involves all the biochemical processes thatcompanion 发表于 2025-3-30 00:39:59
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Excipients as Absorption Enhancers,liver the drug at the right place at the right time and with the right dose with the optimal delivery characteristics. Basically, an excipient has to fulfill the same safety profile as a drug with the exception that it should not exert a therapeutic effect. Most excipients do comply with these requi