Pde5-Inhibitors
发表于 2025-3-28 16:43:43
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食草
发表于 2025-3-28 20:25:54
978-3-319-87680-1Springer International Publishing AG, part of Springer Nature 2017
pancreas
发表于 2025-3-29 02:40:38
Introduction,terestingly, due to direct interactions of acridines with various enzymes, acridines can be suitable drugs for treatment of neurodegenerative diseases, inflammation, immunological disorders, protozoal diseases, etc. General introduction to the field of acridines is provided including scope and limit
DUST
发表于 2025-3-29 03:08:46
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Ferritin
发表于 2025-3-29 08:18:00
Interactions of Acridines with Nucleic Acids,cids (intercalation). Use of multiple acridines in one molecule can cause polyintercalation and enhanced binding to the nucleic acids. Intercalation is widely employed for targeting of cargos to proximity of nucleic acids. Moreover, when the nucleic acid processing enzymes are inhibited by intercala
Proponent
发表于 2025-3-29 13:25:52
Interactions with Proteins,ridine biological activities are necessary. Biological activities of acridines can be significantly caused by direct interactions with proteins. Acridines interact with proteins both directly or as a component of nucleic acid-acridine complex. Acridines influence the living system by direct interact
万灵丹
发表于 2025-3-29 19:08:42
Applications for Treatment of Neurodegenerative Diseases,he brain. The early stages of aggregation are responsible for toxicity of the protein to neurons. Later, the protein precipitates out from the system and can be unavailable for its original purpose. The diseases are accompanied with higher oxidative stress and accumulation of various metals. Since a
危险
发表于 2025-3-29 22:55:39
Some Application of Selective Toxicities of Acridines,pical diseases caused by protozoal parasites e.g. African sleeping sickness, antibacterial agents for combating e.g. tuberculosis, antiviral agent for combating HIV. Moreover, interactions with immune system can overcome failure of human immune system suppressing either cancer or massive autoimmune
协定
发表于 2025-3-30 00:10:42
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排出
发表于 2025-3-30 07:13:04
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