Ford 发表于 2025-3-21 18:01:18
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Gene Expression-Based Biomarkers of Drug Safety, toxicity for use in preclinical and clinical studies. These biomarkers may have diagnostic and/or predictive values and may consist of single gene products or of gene sets or gene expression signatures. Derivation and validation of these molecular markers involves supervised classification methodsTransfusion 发表于 2025-3-22 01:58:24
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Real-Time Polymerase Chain Reaction Gene Expression Assays in Biomarker Discovery and Validation,creasingly important role in all phases of drug development as well as regulatory decision making. However, translating biomarker discovery into clinically useful tests in a time- and cost-effective manner remains a significant challenge. Real-time polymerase chain reaction (PCR) technology, in partAids209 发表于 2025-3-22 11:23:26
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The Use of Two-Dimensional Gel Electrophoresis for Plasma Biomarker Discovery, rapidly growing arsenal of proteomics technologies. 2-DE combines two orthogonal and independent electrophoretic steps: isoelectric focusing (IEF) and sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS-PAGE). At present, 2-DE is capable of simultaneously detecting and quantifying up toErgots 发表于 2025-3-22 21:39:16
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