choleric 发表于 2025-3-21 19:20:28
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The Gene-Duplication Problem: Near-Linear Time Algorithms for NNI Based Local Searches,ion events. This problem is NP-complete and thus requires efficient and effective heuristics. Existing heuristics perform a stepwise search of the tree space, where each step is guided by an exact solution to an instance of a local search problem. A classical local search problem is the . ., which i深渊 发表于 2025-3-22 08:04:52
A Distance-Based Method for Detecting Horizontal Gene Transfer in Whole Genomes,me evolution. Methods for detecting horizontal gene transfer from sequence abound. Among the most accurate are methods based on phylogenetic tree inference, but even these can perform poorly in some cases, such as when multiple trees fit the data equally well. In addition, they tend to be computatio避开 发表于 2025-3-22 09:01:27
An Approach for Determining Evolutionary Distance in Network-Based Phylogenetic Analysis,etabolic networks. The differences between networks, often expressed as evolutionary distances, are normally measured using the plain .. In this paper, we show enzymes are different in phylogenetic conservation and topological importance, which are correlated significantly. Inspired by this observatBUST 发表于 2025-3-22 12:58:39
Pairwise Statistical Significance Versus Database Statistical Significance for Local Alignment of Pt programs report the statistical significance of an alignment in context of a database search. This database statistical significance is dependent on the database, and hence, the same alignment of a pair of sequences may be assessed different statistical significance values in different databases.ELATE 发表于 2025-3-22 18:43:39
Estimating Pairwise Statistical Significance of Protein Local Alignments Using a Clustering-Classifwn to follow an extreme value distribution with analytically calculable parameters . and . for ungapped alignments with one substitution matrix. But no statistical theory is currently available for the gapped case and for alignments using multiple scoring matrices, although their score distribution单调性 发表于 2025-3-23 00:57:40
Gapped Extension for Local Multiple Alignment of Interspersed DNA Repeats,equence alignment methods have been the prevailing technique to identify homologous nucleotides. However, existing methods that identify and align all homologous nucleotides in one or more genomes have suffered poor scalability and limited accuracy. We propose a novel method that couples a gapped exnerve-sparing 发表于 2025-3-23 01:53:52
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