是限制 发表于 2025-3-23 12:29:58
James Gacek,David Ireland,Richard Jochelsonetermined through direct experimentation for each helicase; however such data by itself cannot definitively demonstrate the actual . substrate for a given helicase. Helicases are thought to act as multimers, typically either dimers or hexamers (4).羽饰 发表于 2025-3-23 14:44:20
http://reply.papertrans.cn/19/1867/186670/186670_12.pngEnervate 发表于 2025-3-23 19:57:48
https://doi.org/10.1007/978-3-030-30453-9ologous chromosomes. Thus the genome instability observed in BS may involve perturbations in the activities of DNA topoisomerases, in addition to defects in BLM itself..This chapter is a modified version of a manuscript representing an equal contribution between Brad Johnson and myself. Much of themastopexy 发表于 2025-3-24 00:58:34
http://reply.papertrans.cn/19/1867/186670/186670_14.png全面 发表于 2025-3-24 05:19:11
James Gacek,David Ireland,Richard Jochelsonive helicases, this vast group of proteins has been divided into several superfamilies; the sole common sequence motif shared among all superfamilies is a nucleoside binding domain, termed the Walker box (1), a sequence also found in many proteins that do not function as helicases. However, helicase延期 发表于 2025-3-24 06:56:18
Introduction: Beware of Justice,nd encodes a novel member of the RecQ DNA helicase family. Here the cloning of a highly conserved murine homolog of WRN, mWRN, is described. Unlike the human WRN protein, which is concentrated in the nucleolus, mWRN is distributed throughout the nucleus. Mice lacking the mWRN protein are viable andBRIEF 发表于 2025-3-24 14:17:47
http://reply.papertrans.cn/19/1867/186670/186670_17.pngPHIL 发表于 2025-3-24 15:58:37
Justice over the Course of Lifety to cancer. The gene product defective in NBS, p95, associates with two other proteins, Mre11 and Rad50, and these proteins form foci following irradiation (termed IRIFs). Here we demonstrate that in the absence of DNA damage, a portion of p95 and Mre11 is concentrated in PML Nuclear Bodies (NBs);碌碌之人 发表于 2025-3-24 19:27:45
http://reply.papertrans.cn/19/1867/186670/186670_19.pngTHROB 发表于 2025-3-25 01:32:51
https://doi.org/10.1007/978-1-4615-1405-3DNA; Mutation; Nucleoside; Telomere; biochemistry; biology; cancer; chemistry; development; enzymes; genes; gen