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In Vivo Determination of Kinetic Parameters for Glucose Influx and Efflux by Means of 3-O-11C-Methyrfusion. The second parameter should relate to tissue metabolism, for example, to the glucose utilisation rate (Sokoloff et al. 1977, Phelps et al. 1979, Kuhl et a1.1980) or to the local unidirectional glucose transport rate (Vyska et al. 1980, Vyska et al. 1981, Vyska et al. 1982, Vyska et al. 1983, Kloster et al. 1981).