分期 发表于 2025-3-21 18:41:25
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Environmental influences affecting the voluntary intake of drugs: an overviewimple, but the bitter taste of many drugs requires that the animals first be forced to consume treated water. The intravenous route, wherein relatively unrestrained rats or monkeys press a lever to obtain intravenous drugs, permits precise control over the dose and can be readily adapted to schedule舰旗 发表于 2025-3-22 04:16:09
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Second-order schedules of drug injectionevery 30th response produced an injection; steady responding at high rates of over one per second were maintained during each fixed-ratio component. Under a fixed-interval schedule, the first response occurring after a fixed time of 5 min produced an injection; there was a pause at the start of each打谷工具 发表于 2025-3-22 10:55:30
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Behavioral correlates of serotonin depletionchlorophenylalanine produces an increased sensitivity to pain as measured by the flinch-jump, stabilimetric, or hot-plate methods. Examination of the effects of a number of other lesions and drugs indicated that dopamine, norepinephrine and acetylcholine are not involved in pain sensitivity. Dosagescorpuscle 发表于 2025-3-23 00:53:51
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Catecholamines and drug—behavior interactionsconditions that maintain the behavior. For example, the effects of amphetamine and alpha-methyl-.-tyrosine (αMT) on operant performances depend to a large extent on the rate at which organisms respond under nondrug control conditions. A neurochemical mechanism for these rate-dependent effects has no