PAC
发表于 2025-3-26 22:20:27
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玉米棒子
发表于 2025-3-27 03:13:05
,Therapeutic Strategies for Huntington’s Disease,gnitive, motor, and psychiatric impairment. This review focuses on the current state of therapeutic development for the treatment of HD, including the preclinical and clinical development of small molecules and molecular therapies.
insurgent
发表于 2025-3-27 06:28:14
Comparing Results to Regression Resultsgnitive, motor, and psychiatric impairment. This review focuses on the current state of therapeutic development for the treatment of HD, including the preclinical and clinical development of small molecules and molecular therapies.
贪婪的人
发表于 2025-3-27 11:02:11
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拖网
发表于 2025-3-27 14:57:48
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gastritis
发表于 2025-3-27 18:34:19
,Large Animal Models of Huntington’s Disease, patient brains. Since there are considerable species differences between small and large animals, large animal models of Huntington’s disease may allow one to identify the pathological features that are more similar to those in patients and also help uncover more effective therapeutic targets. This
Fretful
发表于 2025-3-27 23:16:54
,Viral Vector-Based Models of Parkinson’s Disease,ssion of α-synuclein are the most prevalent and extensively studied, and therefore the main focus of this chapter. Many efforts have been made to increase the expression levels of α-synuclein in the dopaminergic neurons. The best α-synuclein models currently available have been developed from a comb
刺激
发表于 2025-3-28 02:48:06
Transgenic Rodent Models to Study Alpha-Synuclein Pathogenesis, with a Focus on Cognitive Deficits,ated using rodent models. There are currently several lines of transgenic mice overexpressing wild-type or mutated aSyn under various promoters. This review will provide an updated synopsis of the mouse lines available, summarize their cognitive deficits, and reflect on how deficits observed in thes
独裁政府
发表于 2025-3-28 08:28:13
Models of Multiple System Atrophy,nisms of neurodegeneration and GCIs formation, which is paralleled by a lack of therapeutic strategies. Two main types of rodent models have been generated to replicate different features of MSA neuropathology. On one hand, neurotoxin-based models have been produced to reproduce neuronal loss in sub
lipids
发表于 2025-3-28 12:27:39
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